If you're an active Adsense publisher, I'm sure you have
seen irrelevant Adsense ads on your site. Right? I've
experienced them too.

Not only these ads do not relate to your website content,
they will not get clicked as well.

Recently I've figured out several ways how to solve this
problem.

1- Try adding META tags to your web page. The most
important tags are TITLE, DESCRIPTION and KEYWORDS.

2- Rename your html file. Don't use a generic name.
Instead, use your keyword(s) as your file name. For
example, if the page is about making money with Adsense,
simply name it make-money-with-adsense.htm.

3- Try refreshing your page again and again until you see
relevant ads displayed. You can refresh the page by
clicking on the refresh button, or pressing F5 key on your
keyboard.

4- If any of the above tricks do not work, you can send an
email to Google Adsense Support telling them about the
problem. Don't hesitate. Their support team will reply to
your email shortly.

I've experienced this problem with several sites of mine,
and it was solved 2-3 days after contacting Google Adsense
team.